Sporulation of a Bacitracin-sensitive Mutant of Bacillus licheniformis Is Self-inhibited by Bacitracin
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منابع مشابه
Enhanced Production of Bacitracin by a Mutant Strain Bacillus Licheniformis Uv-mn-hn-8 (enhanced Bacitracin Production by Mutagenesis)
The present study is focused on the improvement of Bacillus licheniformis through random mutagenesis to obtain mutant having enhanced production of bacitracin. Many isolates of Bacillus licheniformis were isolated and the isolate GP-40 produced maximum bacitracin production (16±0.72 IU/mL). Treatment of Bacillus licheniformis GP-40 with ultraviolet (UV) radiations increased bacitracin productio...
متن کاملFormation of Bacitracin by Washed Cell Suspensions of Bacillus Licheniformis.
Although the microbial formation of a variety of polypeptides possessing antibiotic activities has been known for some time, the biosynthesis of these compounds has as yet received little attention. Not only is the mechatnism of formation of these biologically active compounds of interest in itself, but the biosyntheses of these polypeptides are potential systems for investigating the general p...
متن کاملThe production of bacitracin synthetase by Bacillus licheniformis ATCC 10716.
Bacitracin synthetase is an enzyme complex [ 1,2] composed of three complementary fractions called A, B and C [3] (see fig.1). F’hosphopantetheine which is covalently bound to the fractions [2,3,.5] is probably involved in the biosynthesis of bacitracin. Similar to gramicidin S and tyrocidine [6] its mechanism of synthesis has been described as a thiotemplate mechanism [7]. In the present work ...
متن کاملSystematic mutagenesis method for enhanced production of bacitracin by Bacillus licheniformis Mutant Strain UV-MN-HN-6
The purpose of the current study was intended to obtain the enhanced production of bacitracin by Bacillus licheniformis through random mutagenesis and optimization of various parameters. Several isolates of Bacillus licheniformis were isolated from local habitat and isolate designated as GP-35 produced maximum bacitracin production (14±0.72 IU ml(-1)). Bacitracin production of Bacillus lichenif...
متن کاملProtoplast Lysis and Inhibition of Growth of Bacillus Licheniformis by Bacitracin.
Snoke, John E. (University of California, Los Angeles), and Neal Cornell. Protoplast lysis and inhibition of growth of Bacillus licheniformis by bacitracin. J. Bacteriol. 89:415-240. 1965.-The growth of Bacillus licheniformis is inhibited by bacitracin, the antibiotic which the organism itself produces. The effect of the antibiotic is confined to the early growth phase of the organism. Bacitrac...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1989
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-135-11-2813